**Preheat the Oven:** Preheat your oven to 375°F (190°C). Line a baking sheet with parchment paper or aluminum foil for easy cleanup.
**Prepare the Brown Sugar Rub:** In a mixing bowl, combine brown sugar, smoked paprika, garlic powder, onion powder, salt, and black pepper.
**Coat the Chicken Tenders:** Pat the chicken tenders dry with paper towels. Rub the brown sugar mixture evenly over each tender, ensuring a generous coating.
**Arrange and Brush:** Place the coated tenders on the prepared baking sheet, spacing them out evenly. Brush each tender with melted butter for added flavor and moisture.
**Bake:** Bake for 20-25 minutes, flipping halfway through, until the tenders are golden and caramelized. Ensure they reach an internal temperature of 165°F (74°C).
**Serve:** Allow the tenders to rest for 5 minutes before serving. Enjoy them as-is or with your favorite dipping sauce.