**Preheat the Oven:**
Preheat your oven to 375°F (190°C). Lightly grease a baking dish with cooking spray or a small amount of melted butter.
**Prepare the Shrimp:**
Place the shrimp in the prepared baking dish in a single layer.
**Make the Garlic Butter:**
In a small bowl, whisk together the melted butter, minced garlic, and chopped parsley. Pour the mixture evenly over the shrimp.
**Prepare the Topping:**
In another bowl, mix the Parmesan cheese, panko breadcrumbs, paprika, black pepper, and red pepper flakes (if using). Sprinkle this mixture evenly over the shrimp.
**Bake the Shrimp:**
Bake in the preheated oven for 12-15 minutes, or until the shrimp turn pink and opaque and the topping is golden brown.
**Serve:**
Remove from the oven and garnish with additional parsley and a squeeze of fresh lemon juice. Serve hot with lemon wedges on the side.