Swiss Chicken Casserole is a comforting and creamy baked dish that brings together tender chicken, melty Swiss cheese, and a savory stuffing topping.

This easy-to-make recipe is perfect for weeknight dinners or potlucks, delivering hearty flavors that the whole family will love. The combination of creamy soup, flavorful cheese, and buttery stuffing makes this casserole irresistible and satisfying.

Kitchen Equipment Needed:

9×13-inch baking dish
Mixing bowls
Whisk
Spatula
Measuring cups and spoons

Ingredients:

4 boneless, skinless chicken breasts (about 2 pounds)
6–8 slices Swiss cheese
1 (10.5-ounce) can cream of chicken soup
1/2 cup sour cream or plain Greek yogurt
1/4 cup milk
1 (6-ounce) box stuffing mix (such as Stove Top)
1/4 cup unsalted butter, melted
1 teaspoon garlic powder
1/2 teaspoon onion powder
Salt and pepper, to taste

Directions:

1. Preheat the oven:

Preheat your oven to 375°F (190°C). Grease a 9×13-inch baking dish or spray it with cooking spray.

2. Prepare the chicken:

Season the chicken breasts with garlic powder, onion powder, salt, and pepper. Arrange them in a single layer in the prepared baking dish.

3. Add the cheese:

Place slices of Swiss cheese over each chicken breast, covering the surface evenly.

4. Make the creamy sauce:

In a mixing bowl, whisk together the cream of chicken soup, sour cream, and milk until smooth. Pour the mixture evenly over the chicken and cheese.

5. Prepare the stuffing topping:

In a separate bowl, combine the stuffing mix with the melted butter. Toss until the stuffing is evenly coated. Spread the stuffing mixture over the top of the casserole.

6. Bake:

Cover the dish with aluminum foil and bake for 30 minutes. Remove the foil and bake for an additional 15–20 minutes, or until the chicken is cooked through (internal temperature of 165°F/74°C) and the stuffing is golden brown.

7. Rest and serve:

Let the casserole rest for 5 minutes before serving. Enjoy as is or pair with a side of green beans or a crisp salad.

Prep Time:

15 minutes

Cook Time:

45–50 minutes

Total Time:

1 hour

Nutrition (per serving):

Calories: 420
Protein: 38g
Fat: 18g
Carbohydrates: 22g
Fiber: 1g
Sugar: 2g

Expert Tips:

Thin chicken breasts: If your chicken breasts are thick, consider pounding them to an even thickness for quicker and more even cooking.
Cheese options: Swap Swiss cheese for provolone or mozzarella if you prefer a milder flavor.
Stuffing mix: Use your favorite flavor of stuffing mix, such as herb-seasoned or cornbread, to customize the dish.

FAQs:

Can I use chicken thighs instead of breasts?
Yes, boneless, skinless chicken thighs work well and stay moist during baking.

Can I make this casserole ahead of time?
Yes, assemble the casserole (except for the stuffing topping) and refrigerate it for up to 24 hours. Add the stuffing mix just before baking.

What sides pair well with Swiss Chicken Casserole?
Steamed broccoli, roasted vegetables, or mashed potatoes complement this dish beautifully.

Storing & Reheating:

Storing: Store leftovers in an airtight container in the refrigerator for up to 3 days.
Reheating: Reheat individual portions in the microwave or the entire casserole in a 350°F (175°C) oven until warmed through.
Freezing: Freeze the assembled casserole (before baking) for up to 2 months. Thaw overnight in the refrigerator before baking.

Substitutions & Variations:

Gluten-free: Use a gluten-free stuffing mix and cream of chicken soup.
Vegetarian: Replace the chicken with cooked, sliced mushrooms or zucchini rounds for a meat-free option.
Low-fat option: Use reduced-fat cheese, soup, and sour cream for a lighter version.

Swiss Chicken Casserole